Table 1.
Differentially Regulated Proteins
| Protein Name | Accession Number |
Spot Number | MW (kD) |
||
|---|---|---|---|---|---|
| pI | Av ratio | t-test | |||
| 6 hr vs Con | |||||
| ER proteins | |||||
| Hypoxia up-regulated protein 1(grp170) | HYOU1_HUMAN | 1 | 111 | ||
| 5.2 | 1.24 | 0.0014 | |||
| GRP78 (BiP or HSPA5) | GRP78_HUMAN | 8, 9 & 10 | 72 | ||
| 5.1 | 1.69 | 0.0037 | |||
| PDI isoenzyme A1 | PDIA1_HUMAN | 12 | 57 | ||
| 4.8 | 1.53 | 8.40E-05 | |||
| Endoplasmin (grp 94) | ENPL_HUMAN | 12 | 92 | ||
| 4.7 | 1.53 | 8.40E-05 | |||
| Procollagen lysyl-hydroxylase | PLOD2_HUMAN | 3 &4 | 85 | ||
| 6.2 | 1.66 | 0.00078 | |||
| Cytoskeleton-associated proteins | |||||
| Filamin-A | FLNA_HUMAN | 3 &4 | |||
| 1.66 | 0.00078 | ||||
| Heat shock protein beta-1(hsp27) | HSPB1_HUMAN | 20 | 23 | ||
| 6.0 | 1.74 | 0.0028 | |||
| Programmed cell death 6 interacting protein | PDCD6IP_HUMAN | 3 &4 | 96 | ||
| 6.1 | 1.66 | 0.00078 | |||
| (also known as ALIX) | |||||
| Lamin-A/C, | LMNA_HUMAN | 11 | 74 | ||
| 6.6 | −1.3 | 0.019 | |||
| Dihydropyrimidinase-like 2 | DPYSL2_HUMAN | 11 | 62 | ||
| 5.9 | −1.3 | 0.019 | |||
| Vimentin | VIME_HUMAN | 16 | 54 | ||
| 5.1 | −4.5 | 0.0075 | |||
| F-actin capping protein subunit alpha-1 | CAPZA1_HUMAN | 18 | 33 | ||
| 5.4 | −2.27 | 3.30E-06 | |||
| Stathmin | STMN1_HUMAN | 22 | 17 | ||
| 5.7 | −1.53 | 0.002 | |||
| Translation | |||||
| Eukaryotic translation initiation factor 4 | IF4A1/2_HUMAN | 14 | 46 | ||
| 5.3 | 1.46 | 0.0013 | |||
| Ribosomal protein S3 | RPS3_HUMAN | 19 | 27 | ||
| 9.7 | 1.34 | 0.015 | |||
| Miscellaneous | |||||
| Dipeptidyl-peptidase 3 | DPP3_HUMAN | 8, 9 & 10 | 83 | ||
| 5.0 | 1.69 | 0.0037 | |||
| Trifunctional enzyme subunit beta | HADHB_HUMAN | 14 | 51.3 | ||
| 9.4 | 1.46 | 0.0013 | |||
| Protein CDV3 homolog | CDV3_HUMAN | 19 | 27 | ||
| 6.1 | 1.34 | 0.015 | |||
| Hsp90 | HS90A_HUMAN | 8, 9 & 10 | 85 | ||
| 4.9 | 1.69 | 0.0037 | |||
| Deoxyuridine triphosphatase | DUT_HUMAN | 21 | 27 | ||
| 9.6 | −1.36 | 0.031 | |||