TABLE 3.
Pearson correlation coefficients between tobacco dependence, cigarette consumption, and tobacco biomarkers in Black and White smokers by tobacco dependence
| Variable | Group | NNAL | Total PAH | NEq | Urine COT | Plasma COT |
|---|---|---|---|---|---|---|
| FTND | Black smokers | |||||
| low dependence | −0.15 | −0.21 | −0.20 | 0.04 | 0.08 | |
| high dependence | −0.07 | 0.16 | −0.01 | −0.20 | −0.05 | |
| White smokers | ||||||
| low dependence | 0.52 | 0.41 | 0.46 | 0.20 | 0.16 | |
| high dependence | 0.16 | 0.25 | 0.30 | 0.26 | 0.27 | |
|
| ||||||
| TFC | Black smokers | |||||
| low dependence | 0.09 | 0.00 | −0.10 | −0.10 | −0.04 | |
| high dependence | −0.02 | −0.21 | −0.02 | −0.01 | −0.15 | |
| White smokers | ||||||
| low dependence | −0.34 | −0.31 | −0.35 | −0.30 | −0.25 | |
| high dependence | −0.11 | −0.14 | −0.13 | −0.05 | −0.25 | |
|
| ||||||
| CPD | Black smokers | |||||
| low dependence | −0.03 | 0.03 | −0.25 | −0.19 | −0.09 | |
| high dependence | −0.12 | 0.1 | 0.02 | 0.16 | 0.15 | |
| White smokers | ||||||
| low dependence | 0.33 | 0.38 | 0.36 | 0.21 | 0.38 | |
| high dependence | 0.14 | 0.12 | 0.18 | −0.05 | 0.22 | |
|
| ||||||
| NEq | Black smokers | |||||
| low dependence | 0.77 | 0.61 | 1 | 0.69 | 0.76 | |
| high dependence | 0.39 | 0.73 | 1 | 0.68 | 0.72 | |
| White smokers | ||||||
| low dependence | 0.63 | 0.64 | 1 | 0.78 | 0.74 | |
| high dependence | 0.61 | 0.59 | 1 | 0.72 | 0.57 | |
NOTGES: Tobacco dependence was measured by time to first cigarette (TFC) (median = 15 min); low tobacco dependence = TFC >15 min; high tobacco dependence = TFC ≤ 15 min; Black, low dependence, n = 28; Black, high dependence, n = 41; White, low dependence, n = 57; White, high dependence, n = 78; NNAL = 4-(methylnitrosamino)-1-(3)pyridyl-1-butanol; total PAH = polycyclic aromatic hydrocarbon metabolites; NEq = nicotine equivalent; CPD = cigarettes per day; Fluor is molar sum of 1-, 2-, and 3-fluorenols; COT is cotinine; all biomarker data were log10-transformed; significant correlations are in bold.