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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Dev Dyn. 2013 Feb;242(2):132–147. doi: 10.1002/dvdy.23910

Figure 3. N-Myc has more effect than L-Myc in Pax2-expressing organ development.

Figure 3

Pax2 is expressed in the inner ear, kidney and cerebellum but not in the forebrain. Area measurement of these organs in P0 control (blue), L-Myc CKO (red), N-Myc CKO (green) and dCKO (purple) mice reveal that all three mutant mice have decreased cross sectional area compared to control for Pax2-expressing regions, but there is no change in size of the forebrain, a non-Cre expressing region. In addition, N-Myc CKO and dCKO mice have greater size reduction than L-Myc CKO alone in all the Pax2-expressing regions. Error bars are standard error of the mean. N= 6 for each measurement.