Figure 5. Regulation of Genes Affecting GABAergic Transmission.
Data were analyzed as described for Figure 4. The transcripts encoding glutamic acid decarboxylase 65 and 67 (Gad1 and Gad2) are expressed at similar levels. GABA transport into synaptic vesicles requires Slc36a1; retrieval of GABA from extracellular space requires Slc6a1, Slc6a13, or Slca11. Multiple ionotropic GABAA receptor subunits are expressed in the NAc; expression of metabotropic GABAB receptor Gabbr1 greatly exceeds expression of Gabbr2.