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. 2013 Jan 24;3:494. doi: 10.3389/fphys.2012.00494

Table 4.

Parameter values identified using experimental data on sodium and urea kidney concentrations, fluid reabsorption, urine flow, and sodium as well as urea urine concentration for a normal hydration state.

Parameter Identified value
WATER CONDUCTIVITY [L2/(min μmol)]
R (iInline graphic Proximal tubule) 1.2E−7
R (iInline graphic Descending Henle’s loop in outer Medulla) 2.7E−11
R (iInline graphic Descending Henle’s loop in inner Medulla I) 2.35E−10
R (iInline graphic Descending Henle’s loop in inner Medulla II) 1.0E−12
R (iInline graphic Distal tubule) 6.77E−8
R (iInline graphic Collecting duct in cortex) 7.406E−9
R (iInline graphic Collecting duct in outer medulla) 5.078E−9
R (iInline graphic Collecting duct in inner medulla I) 1.164E−9
R (iInline graphic Collecting duct in inner medulla II) 4.443E−11
RATE CONSTANTS SODIUM TRANSPORT (L/min)
kactive (iInline graphic Proximal tubule) 2.48E−4
kactive (iInline graphic Ascending Henle’s loop in outer medulla) 7.87E−4
kactive (iInline graphic Distal tubule) 5.11E−4
RATE CONSTANTS SODIUM DIFFUSION (L/min)
kpassive (iInline graphic Ascending Henle’s loop in inner medulla II) 2.5E−3
kpassive (iInline graphic Ascending Henle’s loop in inner medulla I) 2.5E−3
RATE CONSTANTS UREA DIFFUSION (L/min)
kpassive (iInline graphic Proximal tubule) 8.2E−9
kpassive (iInline graphic Ascending Henle’s loop in inner medulla II) 4.89E−6
kpassive (iInline graphic Collecting duct in inner medulla I) 1.39E−6
kpassive (iInline graphic Collecting duct in inner medulla II) 4.45E−5
SURFACE AREA DVR (cm2)
S (jInline graphic Outer medulla) 1.0E−3
S (jInline graphic Inner medulla I) 1.0E−4
S (jInline graphic Inner medulla II) 1.0E−4

The values for water conductivities and rate constants refer to the long loop nephrons. The values for short loop nephrons are obtained by scaling the values for the long loop nephrons by the ratio of the number of short loop nephrons to the number of long loop nephrons.