Table 2.
Primary and secondary outcome measures of survival in intention-to-treat population
| Outcome | Cilengitide 240 mg/m2 n = 35 | Cilengitide 400 mg/m2 n = 35 | Cilengitide 600 mg/m2 n = 36 | Docetaxel 75 mg/m2 n = 34 |
|---|---|---|---|---|
| Median PFS, days [95 % CI] | 54 [43–64] | 63 [53–66] | 63 [42–67] | 67 [61–123] |
| Median OS, days [95 % CI] | 173 [81–197] | 117 [92–209] | 181 [90–326] | 194 [135–298] |
| 1-year survival rate, % [95 % CI] | 13 [1.2–24.4] | 13 [0.4–25.5] | 29 [12.3–46.5] | 27 [10.4–43.4] |
CI, confidence interval; OS, overall survival; PFS, progression-free survival