Table 2.
Estimated activities from drawn ROIs and uptakes measured by ex vivo weighing and counting derived from 64Cu-DOTA-KS83 (n = 5)
| Organ (%ID/g) | ROI (4 h) | ROI (20 h) | Bio (4 h) | Bio (20 h) |
|---|---|---|---|---|
| HEC1A/EMP2 tumor | 7.6 ± 1.2 | 10.2 ± 2.6 | 7.3 ± 0.5 | 9.7 ± 1.9 |
| Hec1A tumor | 5.6 ± 0.7 | 6.0 ± 0.1 | 5.8 ± 0.8 | 4.2 ± 1.3 |
| Ramos tumor | 2.6 ± 1.0 | 1.9 ± 0.5 | N.D. | 2.3 ± 0.5 |
| Liver | 19.6 ± 1.9 | 19.6 ± 3.5 | 19.2 ± 5.4 | 18.1 ± 1.6 |
| Kidney | 26.8 ± 4.6 | 24.8 ± 5.9 | 47.1 ± 12.4 | 36.4 ± 8.3 |
| Lung | 9.7 ± 1.6 | 4.8 ± 1.2 | 12.5 ± 5.6 | 5.5 ± 1.1 |
| Heart | 13.9 ± 2.8 | 4.2 ± 0.4 | 9.2 ± 0.9 | 4.3 ± 1.0 |
| Soft tissue | 0.7 ± 0.2 | 0.7 ± 0.2 | 1.0 ± 0.4 | 0.8 ± 0.1 |
| Blood | N.D. | N.D. | 18.1 ± 3.0 | 3.7 ± 0.6 |
| Uterus | N.D. | N.D. | 5.4 ± 0.8 | 4.9 ± 1.6 |
Data are expressed as %ID/g ± SD
N.D. not determined