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. 2012 Nov 22;108(1):121–130. doi: 10.1038/bjc.2012.499

Table 2. Clinicopathological variables and BDNF/TrkB expression in 150 gastric cancer patients.

    TrkB expression
  BDNF/TrkB axis
 
Variable n High (n=64) Low (n=86) P Co-expression (n=35) Others (n=115) P
Gender
Male 119 54 65 188b 29 90 0.557b
Female 31 10 21   6 25  
Age (y)
<69 (median) 71 30 41 0.923b 12 59 0.078b
⩾69 79 34 45   23 56  
Tumour size
⩾5.5 cm (median) 76 34 42 0.603b 20 56 0.382b
<5.5 cm 74 30 44   15 59  
Histological type
Intestinal type 75 39 36 0.021a,b 24 51 0.012a,b
Diffuse type 75 25 50   11 64  
Pathological T category
pT1/2 52 18 34 0.146b 9 43 0.204b
pT3/4 98 46 52   26 72  
Venous invasion
+ 119 51 68 0.926b 30 89 0.287b
31 13 18   5 26  
Lymphatic invasion
+ 138 61 77 0.197b 33 105 0.569b
12 3 9   2 10  
Lymph node metastasis
N0 45 14 31 0.061b 5 40 0.021a,b
N1 105 50 55   30 75  
Liver metastasis
H0 138 58 80 0.592b 33 105 0.569b
H1 12 6 6   2 10  
Peritoneal carcinomatosis
P0 123 50 73 0.287b 27 96 0.393b
P1 27 14 13   8 19  
Stage classification
Stage I–II 48 17 31 0.218b 8 40 0.185b
Stage III–IV 102 47 55   27 75  
a

P<0.05.

b

Pearson’s χ2-test.