Table 1. Distribution of HPV16 variant (sub)lineages in cases and controls, by country and region.
| Total |
HPV16 lineages
N
cases/N
controls |
|||||
|---|---|---|---|---|---|---|
| Country/region | N cases/N controls | EUR | As | AFR | AA/NA | P -value a |
| Africa, North | 234/17 | 89/7 | 1/0 | 116/6 | 28/4 | 0.359 |
| Algeria | 109/12 | 57/6 | 1/0 | 35/4 | 16/2 | 1.000 |
| Morocco | 125/5 | 32/1 | — | 81/2 | 12/2 | 0.126 |
| Africa, Sub-Saharan | 43/50 | 1/1 | 0/0 | 42/49 | 0/0 | 1.000 |
| Guinea | 40/25 | 1/0 | — | 39/25 | — | 1.000 |
| Nigeria | 3/25 | 0/1 | — | 3/24 | — | 1.000 |
| America, South/Central | 102/44 | 86/43 | 0/0 | 2/0 | 14/1 | 0.056 |
| Chile | 67/15 | 56/15 | — | 1/0 | 10/0 | 0.342 |
| Argentina | 35/29 | 30/28 | — | 1/0 | 4/1 | 0.366 |
| Asia, East | 258/28 | 37/5 | 181/20 | 11/0 | 29/3 | 0.839 |
| Korea | 47/4 | 7/2 | 35/2 | — | 5/0 | 0.181 |
| Thailand | 211/24 | 30/3 | 146/18 | 11/0 | 24/3 | 0.889 |
| Asia, West | 151/75 | 136/67 | 2/1 | 1/0 | 12/7 | 0.940 |
| India | 101/59 | 95/53 | 2/0 | — | 4/6 | 0.215 |
| Nepal | 24/12 | 22/10 | 0/1 | — | 2/1 | 0.510 |
| Pakistan | 26/4 | 19/4 | — | 1/0 | 6/0 | 0.612 |
| Europe/Central Asia | 333/186 | 324/177 | 0/1 | 0/5 | 9/3 | 0.006 |
| Georgia | 52/3 | 49/3 | — | — | 3/0 | 1.000 |
| Italy | 146/110 | 141/102 | — | 0/5 | 5/3 | 0.039 |
| Poland | 83/26 | 82/26 | — | — | 1/0 | 1.000 |
| Mongolia | 52/47 | 52/46 | 0/1 | — | — | 0.475 |
| Total | ||||||
| 1121/400 | 673/300 | 184/22 | 172/60 | 92/18 | ||
Abbreviations: AA/NA=Asian American/North American; AFR=African; As=Asian; EUR=European.
a
P-value of Fisher’s exact test.