Table 3. Univariate statistical association of mir-124-3 CGI methylation and clinicopathological parameters with recurrence-free survival of patients.

	P- value a	HR	95% CI
mir-124-3 methylation	0.0005	9.37	2.68–32.8
Metastasis	0.0032	4.86	1.7–14
Lymph node status	0.8751	1.18	0.15–9.02
Localised/advanced disease	0.0260	4.28	1.19–15.4
Gender	0.2080	2.11	0.66–32.8
Ageb	0.7058	0.82	0.28–2.35
Diameterb	0.4278	1.67	0.47–5.92

Abbreviations: CI=confidence interval; HR=hazard ratio; CGI=CpG island.

^a Univariate Cox regression analysis.

^b Dichotomisation by the median of parameter.Bold numbers indicate statistical significance (P<0.05).