Table 1. Patients, tumour-related and surgical characteristics of the 49 patients who underwent QC due to EOC relapse.
| Variables | Patients, n (%) |
|---|---|
| N | 49 |
| Median age at surgery (years) | 57 (28–76) |
|
FIGO stage at primary diagnosis
| |
| I | 6 (12.2%) |
| II | 6 (12.2%) |
| III | 33 (67.3%) |
| IV | 1 (2.04%) |
| Histology | |
| Serous-papillary | 33 (67.3%) |
| Mucinous | 1 (2%) |
| Endometriod | 12 (24.5%) |
| Clear cell | 3 (6.1%) |
|
Intraoperative ascites
| |
| None | 33(67.3%) |
| <500 ml | 12 (24.5%) |
| ⩾500 ml | 2 (4.1%) |
|
Grading
| |
| G1 | 3 (6.1%) |
| G2 | 11 (22.4%) |
| G3 | 29 (59.2%) |
|
Median CA125 (U/ml)
| |
| Preoperative | 736 (28–2843) |
| After 3 cycles of chemotherapy | 220 (19–365) |
| After chemotherapy completion | 84 (21–156) |
|
Postoperative tumor residuals
| |
| None | 16 (32.6%) |
| ⩽0.5 cm | 15 (30.6%) |
| 0.5–1 cm | 9 (18.3%) |
| >1 cm | 9 (18.3%) |
|
Years after primary diagnosis
| |
| 2–3 years | 3 (6.1%) |
| 3–5 years | 20 (40.8%) |
| 5–10 year | 14 (28.5%) |
| >10years | 12 (24.5) |
|
Lymph nodes affected
| |
| N0 | 4 (8.2%) |
| N1 | 14 (28.6%) |
| Nx | 31 (63.3%) |
|
Operative procedure
| |
| Peritonectomy | 21 (42.9%) |
| Pelvic LND | 2 (4.1%) |
| Paraaortic LND | 5 (10.2%) |
| Peritonectomy | 21 (43%) |
| Partial liver resection | 3 (6.1%) |
| Liver capsule resection | 1 (2%) |
| Small bowel resection | 25 (51%) |
| Large bowel resection | 21 (42.9%) |
| Partial gastrectomy | 1 (2%) |
| Ileostomy | 10 (20.4%) |
| Colostomy | 6 (12.2%) |
| Cholecystectomy | 2 (4.1%) |
| Splenectomy | 2 (4.1%) |
| Diaphragmatic resection | 1 (2.0%) |
|
Operative morbidity and mortality
| |
| Any major operative complication | 14 (28.6%) |
|
Major complications
| |
| Anastomotic insufficiency | 3 (6.1%) |
| Postoperative fistula formation | 1 (2%) |
| Thromboembolic event | 1 (2%) |
| Infection/sepsis | 9 (18.4%) |
| Postoperative haemorhage | 4 (8.2%) |
|
Symptomatic thrombosis/embolism
| |
| Short bowel syndrome | 1 (2%) |
| Bowel obstruction | 1 (2%) |
| Pneumonia/Pleura effusion | 6 (12.2%) |
| Multiorgan failure | 2 (4.1%) |
| 30-days mortality | 1 (2%) |
Abbreviations: EOC=epithelial ovarian cancer; FIGO=International Federation of Gynecology and Obstetrics; LND=lymph node dissection; QC=quaternary cytoreduction.