Table 1. Patients, tumour-related and surgical characteristics of the 49 patients who underwent QC due to EOC relapse.
Variables | Patients, n (%) |
---|---|
N | 49 |
Median age at surgery (years) | 57 (28–76) |
FIGO stage at primary diagnosis
| |
I | 6 (12.2%) |
II | 6 (12.2%) |
III | 33 (67.3%) |
IV | 1 (2.04%) |
Histology | |
Serous-papillary | 33 (67.3%) |
Mucinous | 1 (2%) |
Endometriod | 12 (24.5%) |
Clear cell | 3 (6.1%) |
Intraoperative ascites
| |
None | 33(67.3%) |
<500 ml | 12 (24.5%) |
⩾500 ml | 2 (4.1%) |
Grading
| |
G1 | 3 (6.1%) |
G2 | 11 (22.4%) |
G3 | 29 (59.2%) |
Median CA125 (U/ml)
| |
Preoperative | 736 (28–2843) |
After 3 cycles of chemotherapy | 220 (19–365) |
After chemotherapy completion | 84 (21–156) |
Postoperative tumor residuals
| |
None | 16 (32.6%) |
⩽0.5 cm | 15 (30.6%) |
0.5–1 cm | 9 (18.3%) |
>1 cm | 9 (18.3%) |
Years after primary diagnosis
| |
2–3 years | 3 (6.1%) |
3–5 years | 20 (40.8%) |
5–10 year | 14 (28.5%) |
>10years | 12 (24.5) |
Lymph nodes affected
| |
N0 | 4 (8.2%) |
N1 | 14 (28.6%) |
Nx | 31 (63.3%) |
Operative procedure
| |
Peritonectomy | 21 (42.9%) |
Pelvic LND | 2 (4.1%) |
Paraaortic LND | 5 (10.2%) |
Peritonectomy | 21 (43%) |
Partial liver resection | 3 (6.1%) |
Liver capsule resection | 1 (2%) |
Small bowel resection | 25 (51%) |
Large bowel resection | 21 (42.9%) |
Partial gastrectomy | 1 (2%) |
Ileostomy | 10 (20.4%) |
Colostomy | 6 (12.2%) |
Cholecystectomy | 2 (4.1%) |
Splenectomy | 2 (4.1%) |
Diaphragmatic resection | 1 (2.0%) |
Operative morbidity and mortality
| |
Any major operative complication | 14 (28.6%) |
Major complications
| |
Anastomotic insufficiency | 3 (6.1%) |
Postoperative fistula formation | 1 (2%) |
Thromboembolic event | 1 (2%) |
Infection/sepsis | 9 (18.4%) |
Postoperative haemorhage | 4 (8.2%) |
Symptomatic thrombosis/embolism
| |
Short bowel syndrome | 1 (2%) |
Bowel obstruction | 1 (2%) |
Pneumonia/Pleura effusion | 6 (12.2%) |
Multiorgan failure | 2 (4.1%) |
30-days mortality | 1 (2%) |
Abbreviations: EOC=epithelial ovarian cancer; FIGO=International Federation of Gynecology and Obstetrics; LND=lymph node dissection; QC=quaternary cytoreduction.