Table 3. Multivariate analysis for OS, postoperative tumour residuals and operative morbidity after quaternary in EOC relapse.

Variable	HR	95% CI	P -value
OSa
Postoperative chemotherapy (yes vs no)b	0.29	0.13–0.65	0.003
Multifocal tumour dissemination (>4 vs ⩽4 number of tumour affected IMO fields)	3.14	1.43–6.9	0.004
Postoperative tumour residualsc
Multifocal tumour dissemination (>4 vs ⩽4 number of tumour affected IMO fields)	11.5	1.17–112.4	0.036
Operative morbidityd
Limited tumour dissemination (⩽4 vs >4 number of tumour affected IMO fields)b	0.082	0.011–0.61	0.015

Abbreviations: CI=confidence interval; EOC=epithelial ovarian cancer; HR=hazard ratio; IMO=intraoperative mapping of ovarian cancer; OS=overall survival.

^a Not significant: grading; G3 vs G1/G2 (P=0.09); ascites: <500 ml vs ⩾500 ml (P=0.41); tumour residuals: none vs any (P=0.65); extrapelvic tumour involvement: yes vs no (P=0.79) and age: <65 vs > 65 years (P=0.49).

^b Protective.

^c Not significant; grading: G3 vs G1/G2 (P=0.37); platinum sensitivity: yes vs no (P=0.46) and extrapelvic tumour involvement: yes vs no (P=0.55).

^d Not significant; grading: G3 vs G1/G2 (P=0.58); extrapelvic tumour involvement: yes vs no (P=0.108), platinum sensitivity: yes vs no (P=0.16) and age: <65 vs >65 years (P=0.99).