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. Author manuscript; available in PMC: 2013 Jan 24.
Published in final edited form as: Nat Med. 2011 Oct 23;17(11):1514–1520. doi: 10.1038/nm.2454

Figure 2. Tumor grafts resembled the original tumors from which they were derived.

Figure 2

A representative ER−PR−HER2− tumor graft (HCI-001) is shown in comparison to the original patient sample. The tumor ID and the original clinical diagnosis for ER, PR, and HER2 are shown at the top. Sections from the patient’s primary breast tumor (patient), and from representative tumor grafts from the same patient (graft). Stains shown are hematoxylin and eosin (H&E) as well as antibody stains for ER, PR, HER2, cytokeratin (CK), E-cadherin (E-cad), β-catenin (β-cat), and human specific vimentin (hVim). Positive antibody signals are brown in color, with hematoxylin (blue) counterstain. Some images are shown at higher magnification to visualize nuclear staining. All scale bars correspond to 100 microns.