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. Author manuscript; available in PMC: 2013 Feb 7.
Published in final edited form as: Phys Med Biol. 2013 Jan 8;58(3):429–449. doi: 10.1088/0031-9155/58/3/429

Figure 3.

Figure 3

Plots summarizing the effect of changing injection order and injection delay on the Pearson correlation coefficient (R) for recovering Knet from dual-tracer TACs as compared to single-tracer TACs. The data are shown for the simulation studies in which 200 pairs of noisy TACs with randomly selected rate parameters were analyzed for dual-tracer versus single-tracer performance. The plot on the left shows results for FDG administered first and FLT after various injection delays, and the plot on the right shows analogous results for FLT administered first. In both cases, recovery of Knet for FLT was highly dependent on the injection delay, improving with increasing delay, whereas recovery of FDG Knet was relatively insensitive to the delay used. Administering FLT first provided significantly better performance for injection delays of 30 min and longer.