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(A) Detectable parasitemia in mice treated with vehicle control (●) or treated with 25 mg/kg CBK201352 (■) twice daily for 10 days; (B) percent survival plots of mouse cohorts treated with 20 mg/kg (▲) once daily and 25 mg/kg (■) twice daily of CBK201352 and untreated (●); (C) weight gain of mice untreated (●) and treated (■) with 25 mg/kg CB201352 twice daily; (D) concentration- and time-dependent killing effect of CBK201352 in vitro.
