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Comparison of ciprofloxacin-susceptible and -resistant E. coli strains. rRNA and pre-rRNA were measured in cultures of an E. coli clinical isolate susceptible to ciprofloxacin (EC103) and three ciprofloxacin-resistant isolates (EC135, EC139, and EC197). The amount of pre-rRNA in strain EC103 was significantly lower than that of the ciprofloxacin-resistant isolates within 15 min after addition of the antibiotic. Error bars estimated the standard deviations.
