Fig 2.

Intestinal histopathology. Shown are representative H&E-stained cecal tissues from infected mice treated or not with vancomycin for 5 days. (A) Uninfected control; (B) infected cecum at day 3; (C) vancomycin treated infection at day 9 (relapse); (D) histopathology scores of cecal tissues of uninfected mice (n = 12), infected mice (n = 16), mice infected and treated with vancomycin (n = 15), and mice infected treated with nitazoxanide (n = 16) moribund (at any day) or sacrificed (at the end of the experiment). *, P < 0.01, and **, P < 0.001, as determined by two-way ANOVA with Bonferroni's correction.