Fig 3.

Clostridial and toxin burdens in cecal contents at peak of infection, post-vancomycin treatment, and at relapse. Mice were infected with VPI 10463 (10⁵) and treated (vanc; n = 9) or not (infected control [IC]; n = 9) with vancomycin. The uninfected group (control) had 9 mice also. Cecal contents and tissues were collected at days 3 (peak of infection), 6 (postvancomycin), 9 (relapse), and 12 (end of experiment). (A) Cecal tcdB shedding; (B) TcdA and TcdB levels in cecal contents; (C) histopathology scores.