Table 5.
Allele frequencies in N-acetyltransferase 2 genes in Cambodia and Tanzaniaa
| Gene | Allele | Cambodia |
Tanzania |
PF | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | % SNP | χ2 | Pχ | n | % SNP | χ2 | Pχ | |||
| NAT2*5 | T/T | 106 | 58 | |||||||
| T/C | 16 | 6.6 | 0.60 | 0.439 | 66 | 36.4 | 0 | 1.000 | <0.003 | |
| C/C | 0 | 19 | ||||||||
| NAT2*6 | G/G | 44 | 84 | |||||||
| G/A | 59 | 40 | 0.01 | 0.920 | 49 | 27 | 3.51 | 0.061 | <0.003 | |
| A/A | 19 | 15 | ||||||||
| NAT2*7 | G/G | 78 | 141 | |||||||
| G/A | 38 | 21 | 0.24 | 0.624 | 7 | 2.4 | 0.09 | 0.764 | <0.003 | |
| A/A | 6 | 0 | ||||||||
| NAT2*14 | G/G | 115 | 107 | |||||||
| G/A | 6 | 2.5 | 0.08 | 0.777 | 27 | 15 | 7.42 | 0.006 | <0.003 | |
| A/A | 0 | 7 | ||||||||
n indicates the number of patients, % SNP is the mutated allele frequency, χ2 is the result from the Hardy-Weinberg equilibrium test, and Pχ is the resulting one-tailed P value. PF is the P value from Fisher's exact test for differences between populations.