Table 5.
RFF based on the accumulation of ethidium bromide for H37Rv and each mutant strain in the presence of efflux inhibitors compared with that for the untreated control (without inhibitor)a
| Strain | RFF for the following efflux inhibitor: |
||
|---|---|---|---|
| CCCP | CPZ | VP | |
| H37Rv | 0.17 | 1.60 | 2.05 |
| MmrKO | 0.21 | −0.05 | 0.46 |
| MmrKO::pCRS5 | 0.08 | 0.53 | 0.61 |
| H37Rv::pCVZ2 | 1.42 | 1.05 | 1.9 |
a
The values correspond to the last point of measurement at 60 min, when fluorescence had reached a steady state. Data correspond to the averages of three independent assays.