Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Amino acid changes in genotype 2a HCV NS5A derived from cells resistant to 60 nM or 1 μM DBPR110
| DBPR110 concn | Amino acid in NS5Aa | Residue in the indicated plasmida |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| p1 | p2 | p3 | p4 | p9 | p6 | p5 | p8 | p9 | ||
| 60 nM | T24 | A | A | A | A | |||||
| P58 | L | L | L | L | ||||||
| 1 μM | Y93 | H | H | H | H | H | H | H | H | H |
p, plasmid derived from DBPR110-resistant individual clone.
