Fig 5.

C57BL/6 mice were infected intragastrically with 1 × 10⁹ CFU wild-type S. Typhimurium or isogenic csgBA mutant or were mock treated (LB) for 72 h. (A and B) Bacterial numbers in the cecal tissue (A) and mesenteric lymph nodes (MLN) (B) were enumerated by plating serial dilutions on medium. (C and D) A similar experiment was conducted with TLR2-deficient animals, and bacterial numbers in the cecal tissue (C) and mesenteric lymph nodes (D) were enumerated. Significant statistical differences are indicated (P < 0.05 or P = 0.0001).