Hematoxylin-and-eosin-stained sections of mouse liver (A, B, and C) and lung (D, E, and F). (A and D) Control group. (B and E) rChxA I-treated group. (C and F) rChxA II-treated group. Severe coagulation necrosis of the hepatocytes and interstitial edema with mild inflammation around the arteriole in lungs can be observed in both the groups treated with either rChxA I or rChxA II. CV, central vein; Br, bronchiole; PA, pulmonary arteriole. Magnification, ×200.