Table 2.
VNTR types among M. intracellulare isolates from patients with nodular bronchiectasis using the seven tandem repeats described by Dauchy et al. (17)a
| VNTR type | Complete tandem repeat no. |
ITS1 (100% identity) | No. of isolates | No. of patientsb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIN22 | MIN20 | MIN18 | MIN19 | MIN33 | MIN31 | MIRU3 | ||||
| 1 | 7 | 2 | 3 | 2 | 2 | 2 | 1 | Min-A | 1 | 1 |
| 2 | 6 | 2 | 3 | 0 | 5 | 2 | 4 | Min-A | 2 | 2 |
| 3 | 5 | 2 | 1 | 1 | 1 | 2 | 2 | Min-A | 7 | 1 |
| 4 | 4 | 4 | 3 | 4 | 3 | 2 | 4 | Min-A | 1 | 1 |
| 5 | 5 | 4 | 3 | 3 | 3 | 2 | 3 | Min-A | 10 | 5 |
| 6 | 4 | 4 | 3 | 3 | 3 | 2 | 2 | Min-A | 4 | 1 |
| 7 | 4 | 4 | 3 | 2 | 3 | 2 | 3 | Min-A | 2 | 2 |
| 8 | 4 | 4 | 1 | 3 | 4 | 1 | 3 | Min-A | 1 | 1 |
| 9 | 4 | 2 | 3 | 3 | 3 | 2 | 3 | Min-A | 4 | 1 |
| 10 | 3a | 4 | 3 | 3 | 4 | 2 | 1 | Min-A | 4 | 3 |
| 11c | 3a | 4 | 3 | 3 | 3 | 2 | 3 | Min-A | 15 | 7 |
| 11a | 3a | 4 | 3 | 2 | 5 | 2 | 1 | Min-A | 1 | 1 |
| 12 | 3a | 4 | 1 | 3 | 3 | 2 | 3 | Min-A | 1 | 1 |
| 13 | 3a | 3 | 3 | 3 | 5 | 2 | 2 | Min-A | 1 | 1 |
| 14 | 3a | 3 | 3 | 3 | 4 | 2 | 3 | Min-A | 5 | 2 |
| 15 | 3a | 3 | 3 | 2 | 3 | 2 | 3 | Min-A | 4 | 1 |
| 16 | 3a | 2 | 3 | 2 | 4 | 2 | 1 | Min-A | 9 | 3 |
| 17 | 3a | 2 | 3 | 2 | 4 | 1 | 3 | Min-A | 1 | 1 |
| 18 | 3a | 2 | 3 | 2 | 3 | 1 | 0 | Min-A | 1 | 1 |
| 19 | 3a | 2 | 1 | 3 + 2 | 3 + 4 | 2 | 2 | Min-A | 3 | 1 |
| 20 | 3a | 2 | 1 | 3 | 3 | 1 | 1 | Min-E (new) (all 3 patients) | 5 | 3 |
| 21 | 3a | 2 | 1 | 1 | 4 | 2 | 0 | Min-A | 4 | 1 |
| 22 | 3a | 1 | 4 | 2 | 3 | 1 | 1 | Min-A | 3 | 1 |
| 23 | 3a | 1 | 3 | 3 | 4 | 2 | 0 | Min-A | 1 | 1 |
| 24 | 3a | 1 | 1 | 3 | 4 | 1 | 2 | Min-A | 9 | 5 |
| 25 | 3a | 12 | 1 | 3 | 4 | 0 | 2 | Min-A | 2 | 1 |
| 26 | 3a | 1 | 1 | 2 | 3 | 1 | 2 | Min-A | 9 | 3 |
| 27 | 3a | 1 | 1 | 1 | 3 | 1 | 2 | Min-A | 1 | 1 |
| 27a | 3a | 0a | 3 | 3 | 4 | 2 | 2 | Min-A | 1 | 1 |
| 28 | 3 | 2 | 1a | 0 | 3 | 2 | 0 | Min-B | 1 | 1 |
| 29 | 2 | 1 | 1 | 3 | 4 | 1 | 2 | Min-A | 1 | 1 |
| 30 | 2 | 1 | 1 | 2 | 4 | 2 | 0 | Min-F (new) | 1 | 1 |
| 31 | 0a | 4 | 3 | 2 | 3 | 2 | 2 | Min-A | 1 | 1 |
| 32 | 0a | 3 | 3 | 3 | 3 | 1 | 0 | Min-A | 1 | 1 |
| 33 | 0a | 3 | 1a | 2 | 4 | 2 | 0 | Min-A | 1 | 1 |
| 34 | 0a | 2 | 3 | 1 | 3 | 2 | 0 | Min-A | 2 | 1 |
| 35 | 0a | 2 | 3 | 3 | 3 | 1 | 0 | Min-A | 2 | 1 |
| 36 | 0a | 2 | 1a | 2 | 2 | 2 | 0 | Min-A | 10 | 3 |
| 37 | 0a | 2 | 1a | 0 | 2 | 2 | 0 | Min-A | 13 | 7 |
| 38 | 0a | 2 | 1 | 1 | 4 | 2 | 0 | Min-A | 13 | 3 |
| 39 | 0a | 0a | 1a | 1 | 1 | 0 | 1 | Min-A | 1 | 1 |
| 40 | 0a | 0a | 1a | 0 | 1 | 0 | 1 | Min-A | 15 | 6 |
| Totals | 176 | 82 | ||||||||
a
Some patients had more than one isolate tested. All VNTR types were validated as M. intracellulare by sequencing of the ITS1 region.
b
Some patients are included in more than one VNTR type.
c
The VNTR type and ITS1 sequence match M. intracellulare ATCC 13950T.