Figure 6.

miR-192 and Atp1b1 abundance in rat kidney cortex in condition of sodium depletion. Rats were fed with a basal diet containing 0.24% sodium (control). One group of animals was then switched to a diet containing 0.03% sodium and maintained on that diet for 48 h. (A) Relative miR-192 expression in kidney cortex, in the two animal groups. After 48 h of low sodium diet, miR-192 was significantly suppressed. n = 5–6/group, *P < 0.05 versus control. (B) Relative Atp1b1 expression in kidney cortex, in the two animal groups. At 48 h of low-salt diet Atp1b1 protein abundance was approximately doubled, although the change did not reach statistical significance. n = 5–6/group.