Table 1.
Possible miRNA-target pairs in PCT and mTAL
| miRNA | Higher expression | Target symbol | Higher expression | Target common name |
|---|---|---|---|---|
| rno-let-7b | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-let-7b | mTAL | Slc22a1 | PCT | Organic cation transporter 1 |
| rno-let-7c | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-let-7e | mTAL | Aqp11 | PCT | Aquaporin 11 |
| rno-let-7e | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-let-7e* | mTAL | Aqp11 | PCT | Aquaporin 11 |
| rno-miR-100 | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
| rno-miR-100 | mTAL | Slc22a6 | PCT | Organic anion transporter 1 |
| rno-miR-132 | mTAL | Aqp1 | PCT | Aquaporin 1 |
| rno-miR-132 | mTAL | Aqp8 | PCT | Aquaporin 8 |
| rno-miR-134 | PCT | Romk2 | mTAL | ATP-sensitive inward rectifier K channel 1.1b |
| rno-miR-150 | mTAL | Lrp2 | PCT | Megalin |
| rno-miR-150 | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-miR-150 | mTAL | Slc22a2 | PCT | Organic cation transporter 2 |
| rno-miR-152 | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
| rno-miR-152 | mTAL | Slc22a2 | PCT | Organic cation transporter 2 |
| rno-miR-16 | PCT | Romk2 | mTAL | ATP-sensitive inward rectifier K channel 1.1b |
| rno-miR-16 | PCT | Umod | mTAL | Uromodulin (Tamm–Horsfall glycoprotein) |
| rno-miR-16 | PCT | Slc12a1 | mTAL | Na(+)-K(+)-2Cl(−) cotransporter |
| rno-miR-16 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-192 | PCT | Atp1b1 | mTAL | Na(+)-K(+)-ATPase beta 1 |
| rno-miR-195 | PCT | Romk2 | mTAL | ATP-sensitive inward rectifier K channel 1.1b |
| rno-miR-195 | PCT | Umod | mTAL | Uromodulin (Tamm–Horsfall glycoprotein) |
| rno-miR-195 | PCT | Slc12a1 | mTAL | Na(+)-K(+)-2Cl(−) cotransporter |
| rno-miR-195 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-20a | mTAL | Aqp1 | PCT | Aquaporin 1 |
| rno-miR-20a | mTAL | Aqp8 | PCT | Aquaporin 8 |
| rno-miR-21 | PCT | Atp1a1 | mTAL | Na(+)-K(+)-ATPase alpha 1 |
| rno-miR-21 | PCT | Umod | mTAL | Uromodulin (Tamm–Horsfall glycoprotein) |
| rno-miR-21 | PCT | Slc12a1 | mTAL | Na(+)-K(+)-2Cl(−) cotransporter |
| rno-miR-21 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-218 | PCT | Atp1b1 | mTAL | Na(+)-K(+)-ATPase beta 1 |
| rno-miR-218 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-23a | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
| rno-miR-23a | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-miR-23b | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
| rno-miR-23b | mTAL | Slc4a4 | PCT | Na(+)/HCO3(−) cotransporter |
| rno-miR-30c | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
| rno-miR-342-3p | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-363 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-363* | PCT | Slc4a2 | mTAL | Anion exchange protein 2 |
| rno-miR-369-3p | PCT | Atp1a1 | mTAL | Na(+)-K(+)-ATPase alpha 1 |
| rno-miR-369-3p | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-382* | PCT | Romk2 | mTAL | ATP-sensitive inward rectifier K channel 1.1b |
| rno-miR-410 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-411 | PCT | Slc12a1 | mTAL | Na(+)-K(+)-2Cl(−) cotransporter |
| rno-miR-411 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-495 | PCT | Romk2 | mTAL | ATP-sensitive inward rectifier K channel 1.1b |
| rno-miR-495 | PCT | Slc4a7 | mTAL | Na(+)-HCO3(−) cotransporter 3 |
| rno-miR-542-3p | PCT | Atp1b1 | mTAL | Na(+)-K(+)-ATPase beta 1 |
| rno-miR-9 | mTAL | Aqp1 | PCT | Aquaporin 1 |
| rno-miR-9 | mTAL | Aqp8 | PCT | Aquaporin 8 |
| rno-miR-9 | mTAL | Aqp11 | PCT | Aquaporin 11 |
| rno-miR-9 | mTAL | Cubn | PCT | Cubilin |
| rno-miR-9 | mTAL | Slc9a1 | PCT | Na(+)/H(+) exchanger 1 |
On the left side are miRNAs and the nephron segment in which they were more highly expressed. On the right side are their predicted protein targets and the nephron segment in which the proteins were more highly expressed. See text for details.