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. 2012 Nov 22;41(2):869–880. doi: 10.1093/nar/gks1077

Figure 2.

Figure 2.

19F NMR (a–c) and CD (d–f) spectra of FABP-, FAF- and FAAF-modified 11-mer duplexes, respectively, in the G*CA and G*CT sequence contexts at 20°C. The B, S and W notation used in the 19F NMR (a–c) signal assignments represent major groove ‘B’, base displaced stacked ‘S’ and minor groove ‘W’ conformers, respectively (see Figure 1c legend). The CD spectra (d–f) of modified duplexes show the typical B-DNA characteristic (positive and negative ellipticity at 275 and 245 nm, respectively) and different ICD290–350 nm patterns represent the lesion conformation in the duplex (see CD in Results).