Table 2.
Frequently recognized antigens in vaccinated subjectsa
| Protein category | Protein | Positive responseb |
||||
|---|---|---|---|---|---|---|
| Humans |
Prairie dogs |
|||||
| DVX (n = 10) | Acam (n = 5) | DVX (n = 11) | Acam (n = 12) | Imvamune (n = 10) | ||
| MV | WR148 | +++ | +++ | +++ | +++ | + |
| WR132 (A13) | +++ | +++ | +++ | +++ | +++ | |
| WR101 (H3) | +++ | +++ | +++ | +++ | +++ | |
| WR113 (D8) | +++ | +++ | +++ | +++ | +++ | |
| WR137 (A17) | +++ | +++ | − | ++ | + | |
| WR150 (A27) | ++ | + | ++ | − | − | |
| WR128 (A9) | − | − | − | ++ | − | |
| EV | WR181 (A56) | − | − | +++ | ++ | − |
| WR187 (B5) | − | ++ | ++ | + | ++ | |
| WR156 (A33) | + | +++ | − | − | − | |
| WR159 (A36) | − | + | + | ++ | − | |
| WR157 (A34) | + | + | − | − | − | |
| Core | WR070 (I1) | +++ | +++ | +++ | +++ | +++ |
| WR129 (A10) | ++ | ++ | +++ | + | +++ | |
| WR123 (A4) | ++ | + | ++ | ++ | − | |
| WR091 (L4) | − | + | ++ | + | ++ | |
| Evasion | WR059 (E3) | − | + | +++ | + | − |
| Other/unknown | WR118 (D13) | +++ | +++ | +++ | +++ | +++ |
| WR130 (A11) | +++ | +++ | +++ | − | +++ | |
| WR169 | + | − | ++ | ++ | ++ | |
a
Proteins with greater than 5 hits over all samples are shown.
b
+, >10% of subjects with a positive response; ++, >25% of subjects with a positive response; +++, >50% of subjects with a positive response; −, no subjects with a positive response.