Table 3.
Changes in antibody targets in vaccinated prairie dogs after challenge with MPXVa
| Protein category | Protein |
|
|---|---|---|
| Prechallenge | Postchallengeb | |
| MV | WR148c, A13, H3, D8 | WR148, A13, H3, D8, A17, A27, A26, A14 |
| EV | None | A56, B5R, F13 |
| Core/enzyme | I1L, A10L | I1, A10, A4, H5, I3, L4, F2, H6, E4 |
| Evasion/virulence | None | E3, A46, C23, B29 |
| Other/unknown | D13L | D13, A11, WR169 |
a
Reactive in greater than 50% of subjects.
b
Underlined proteins were not significantly recognized postvaccination.
c
Absent in Imvamune- but dominant in Dryvax- and Acam2000-vaccinated prairie dogs.