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(A) Functional annotation analysis of genes in cluster 3 indicates that pathways and processes involved in regulating the cell cycle, protein metabolism, immune response, and cell death/apoptosis are enriched in sarcopenia. (B) Quantitative PCR analyses verified upregulation of some of the genes in cluster 3 and candidate genes involved in apoptosis. *, **, ***, and **** indicate P < 0.05, 0.01, 0.001, and 0.0001 versus 6 months, respectively. 6M, 6 months; 12M, 12 months, etc.
