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EV71 3C inhibits promoter activation by IRF7. 293T cells were transfected with IRF7 and GFP-3C along with IFN-β-Luc (A), ISRE-Luc (B), ISG56-Luc (C), and IFN-α4-Luc (D). A plasmid expressing GFP or pRL-SV40 was used as a control. At 24 h after transfection, cell lysates were assayed for luciferase activities. Data are representative of three independent experiments with triplicate samples.
