Fig 7.

Global and local effects of the gH:KV mutations. (A) Ribbon diagram of the H2-H3 domains of HSV-1 gH:wt with the positions of the mutant residues in gH:KV (N753K, A778V) highlighted as space-filling models in magenta and the two halves of the flap represented as dark- and light-blue sticks. (B) Cumulative root mean square deviation (RMSD) from the respective starting structures for the H2-H3 domain of HSV-1 gH:wt and gH:KV. (C) RMSDs of two sides of the flap region, E707-K716 and R717-D726.