Table 1.

Effects on amounts and processing of viral proteins^j

ORF	Deleted or repressed gene				Promotera	TM	Location	Role
	L2b	A11c	A6d	A17e
A3	U	U		U	Intermed	−	Core	MV formation
A4	N	N		N	Early	−	Core	MV formation
A6	D				Intermed	−	Cytoplasm	IV formation
A10	Nf		U		Late	−	MV core	MV formation
A11	D		Ng	N	Late	+	Cytoplasm	IV formation
A13	N		Nh		Late	+	MV membrane	MV formation
A14	D, Gi	D, Gi	Gi		Late	+	IV, MV	IV formation
A16	D				Intermed	+	MV membrane	EFC
A17	U	U			Late	+	IV, MV membrane	IV formation
A21	D	D		D	Late	+	MV membrane	EFC
A26	D	D		D	Late	−	MV membrane	Cell attachment
A27	N				Intermed	−	MV membrane	Cell attachment
A28	D	D		D	Late	+	MV membrane	EFC
A30		N		N	Intermed	−	MV core	MV formation
D8	Nh	N	Nh	N	Intermed	+	IV, MV membrane	Cell attachment
D13	N	N		N	Intermed	−	IV outer	IV scaffold
F9	D	D	D	D	Late	+	MV membrane	EFC
F10	D	D			Late	−	MV core	Kinase, IV formation
F13	N	N		N	Intermed	+	EV membrane	Wrapping
G3	D				Late	+	MV membrane	EFC
G4	N				Intermed	−	MV membrane	Redox
G7	N				Late	−	MV core	Core complex
H2	D				Late	+	MV membrane	EFC
H3	D		Nh		Intermed	+	MV membrane	Cell attachment
H7	N				Intermed	−	Cytoplasm	IV formation
J1	N				Intermed	−	MV core	Core complex
L1	D	D	D	D	Late	+	MV membrane	EFC
L2		N		N	Early	+	ER	IV formation
L5	D				Late	+	MV membrane	EFC

^aData from reference 56.

^bData from present study and reference 37.

^cData from references 37 and 32.

^dData from reference 33.

^eData from reference 37.

^fPrecursor and processed forms not resolved.

^gMislocalized to cytoplasm.

^hER localization.

ⁱGlycosylation and ER localization.

^jAbbreviations: D, decreased; U, unprocessed; N, normal; Intermed, intermediate; TM, transmembrane domain. Shading highlights proteins that are decreased when L2 is repressed or deleted.