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Duration of immunity mediated by D1701-V-RabG. Mice were i.m. immunized once (A), twice (B), or (C) thrice in 3-week intervals (P, prime; B1, boost 1; B2, boost 2) with the indicated amounts (PFU) of D1701-V-RabG. At the indicated weeks after vaccination, the serum VNA titers were determined and are depicted as GMT IU per ml serum. Results after immunization with 105 PFU (black columns), 106 PFU (white columns), and 107 PFU (striped columns) are depicted.
