Fig 1.
WEEV infection induces IFN-β transcription in cultured neurons. BE(2)-C/m cells, hESC-derived neurons, or primary rat cortical neurons were infected with SeV, infectious WEEV, or UV-inactivated WEEV, and IFN-β transcript levels were assessed via qRT-PCR. WEEV was used at an MOI of 1 for both BE(2)-C/m and primary rat neurons and an MOI of 0.1 for hESC-derived neurons, and qRT-PCR was done at 20 to 24 hpi. **, P < 0.005.