Table 4.

Treatment related predictors of impaired body composition, sensation, strength and exercise tolerance among brain tumor survivors

	Obesity		Loss of touch sensation		Leg weakness		Hand weakness		Reduced exercise tolerance
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Tumor location
Posterior fossa	0.7	0.3–2.1	0.3	0.1–1.2	1.2	0.4–3.3	0.4	0.1–1.4	0.9	0.3–3.1
Supratentorial	1.0		1.0		1.0		1.0		1.0
Segmental radiation
Posterior fossa/spine
Yes	0.2	0.1–1.1	2.3	0.3–20.1	1.2	0.2–6.9	2.3	0.2–23.0	1.1	0.1–8.4
None/scatter	1.0		1.0		1.0		1.0
Temporal lobe
Yes	1.7	0.4–8.1	0.6	0.1–4.1	0.9	0.2–3.8	1.0	0.1–8.0	1.5	0.2–10.8
None/scatter	1.0		1.0		1.0		1.0		1.0
Frontal cortex
Yes	1.7	0.3–10.5	1.9	0.2–15.3	3.0	0.5–17.0	2.3	0.3–17.4	2.4	0.4–14.8
None/scatter	1.0		1.0		1.0		1.0		1.0
Occipital/parietal lobe
Yes	3.5	0.5–22.8	0.5	0.1–3.7	0.8	0.2–4.1	0.8	0.1–6.0	3.1	0.5–20.1
None/scatter	1.0		1.0		1.0		1.0		1.0
Received platinum or vincristine
Yes	0.2	0.1–1.1	1.6	0.3–7.1	3.8	0.8–17.8	1.2	0.3–5.6	0.8	0.2–3.3
No	1.0		1.0		1.0		1.0		1.0
Age at diagnosis
< 5 years	4.2	0.9–18.4	2.3	0.7–7.9	0.8	0.3–2.6	4.7*	1.4–16.2	5.8*	1.7–20.7
5–20 years	1.0		1.0		1.0		1.0		1.0

^*Estimates are statistically significant at p < 0.01