Table 2.

Relative Risks (95% confidence intervals) of Parkinson Disease According to Amount of Caffeinated Coffee, Decaffeinated Coffee and Tea at Baseline

Caffeinated Coffee
	Cases	PY	RR *Crude	RR**	p- trend
Men
Never	67	83259	1.00 (Ref)	1.00 (Ref)
<=1/week	43	62782	0.87 (0.59, 1.28)	0.82 (0.55, 1.21)
2–6/week	20	36440	0.70 (0.42, 1.16)	0.65 (0.39, 1.07)
1/day	21	45580	0.55 (0.33, 0.90)	0.50 (0.30, 0.84)
2+/day	46	104796	0.56 (0.38, 0.82)	0.54 (0.37, 0.80)	0.0004
Women
Never	44	147403	1.00 (Ref)	1.00 (Ref)
<=1/week	24	79007	1.03 (0.62, 1.69)	1.00 (0.61, 1.65)
2–6/week	11	39177	0.94 (0.48, 1.82)	0.91 (0.47, 1.77
1/day	16	70275	0.76 (0.43, 1.34)	0.73 (0.41, 1.31)
2+/day	25	118640	0.70 (0.43, 1.14)	0.69 (0.42, 1.15)	0.09
Decaffeinated Coffee
Men
Never	68	110633	1.00 (Ref)	1.00 (Ref)
<=1/week	51	92652	0.87 (0.60, 1.25	0.81 (0.56, 1.17)
2–6/week	26	41458	1.02 (0.65, 1.61	0.94 (0.60, 1.49)
1/day	23	36044	1.01 (0.63, 1.63)	0.95 (0.59, 1.54)
2+/day	26	51160	0.83 (0.53, 1.31)	0.81 (0.51, 1.27)	0.68
Women
Never	32	143680	1.00 (Ref)	1.00 (Ref)
<=1/week	37	135455	1.26 (0.78, 2.03)	1.21 (0.75, 1.95)
2–6/week	18	57024	1.41 (0.79, 2.52)	1.34 (0.75, 2.40)
1/day	22	55212	1.78 (1.03, 3.08)	1.71 (0.99, 2.96
2+/day	11	62138	0.81 (0.41, 1.61)	0.80 (0.40, 1.59)	0.58
Tea
Men
Never	74	123254	1.00 (Ref)	1.00 (Ref)
<=1/week	89	140803	1.08 (0.79, 1.47)	1.03 (0.75, 1.40)
2–6/week	19	35469	0.90 (0.54, 1.50)	0.85 (0.51, 1.41)
1+/day	15	31916	0.74 (0.42, 1.31)	0.72 (0.40, 1.27)	0.19
Women
Never	37	127958	1.00 (Ref)	1.00 (Ref)
<=1/week	53	205842	0.89 (0.59, 1.36)	0.87 (0.57, 1.33)
2–6/week	17	59973	0.91 (0.51, 1.63)	0.87 (0.49, 1.56)
1+/day	13	58036	0.77 (0.41, 1.44)	0.75 (0.40, 1.41)	0.43

^*Crude: adjusted for age

^**adjusted for age, smoking (pack years in 1992 and yes/no in 1999), and alcohol intake (1999)