FIG. 4.

GIP is expressed in pancreatic β-cells in Gcg^gfp/gfp mice, but not in Gcgr^−/−, Glp1r^−/−, or Gcgr^−/−Glp1r^−/− mice. A: Representative immunostaining for GIP (red) and insulin (green), and GFP fluorescence (green) of islets from Gcg^gfp/gfp mice and Gcg^gfp/+ mice. B: Representative immunostaining for GIP (red) and glucagon (green) of islets from Gcgr^−/−, Glp1r^−/−, and Gcgr^−/−Glp1r^−/− mice. Scale bar, 100 µm. (A high-quality digital representation of this figure is available in the online issue.)