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. 2013 Jan 17;62(2):373–381. doi: 10.2337/db12-0202

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© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — Long-term (120-min) coinfusion of GLP-1 and GLP-2 results in decreased postprandial lipemia. A: Chow-fed hamsters received an oral fat load followed by a 120-min infusion (intravenous) of either VEH, GLP-1, GLP-2, or GLP-1 and GLP-2; poloxamer was given 20 min post–fat load (intraperitoneal). Plasma was collected at 30, 60, 90, and 120 min post–fat load to assess TRL-apoB48. B: A representative blot of apoB48 is shown along with a graph of apoB48 levels quantified by densitometry. Plasma (C), TRL-TG (D), and TRL-cholesterol (E) levels were also quantified. Each graph represents the mean ± SEM at each time point for the given parameter. Calculated slopes are shown within each graph (n = 4–5; *P < 0.05 vs. GLP-1, #P < 0.05 vs. GLP-2, ^P < 0.05 vs. GLP-1 + GLP-2).