Immunological and metabolic improvements induced through whole-grain consumption. Plasma IL-6 levels in the entire subject population (a), in overweight participants (b), and in females (c). Maximum postprandial glucose levels in the entire subject population (d) and overweight subjects (e) during the three treatments (BR, BR+WGB, WGB) and at baseline. *P< 0.05, **P< 0.01, §P< 0.1.