Table 1.
Oxidative stress markers of albino rats
| Parameter | Control | Pb | Pb + VC | Pb + VE | Pb + VC + VE |
|---|---|---|---|---|---|
|
GSH (U/mg Protein) |
0.69 ± 0.04 |
0.10 ± 0.02 a |
0.51 ± 0.03 ab |
0.52 ± 0.03 ab |
0.57 ± 0.02 ab |
|
SOD (U/mg Protein) |
9.19 ± 0.69 |
1.20 ± 0.17 a |
5.40 ± 0.43 ab |
6.04 ± 0.55 ab |
6.17 ± 0.07 ab |
|
CAT (U/mg Protein) |
42.48 ± 2.37 |
9.48 ± 0.36 a |
28.90 ± 0.78 ab |
26.44 ± 1.33 ab |
31.30 ± 0.69 ab |
|
MDA (Mmol/g tissue) |
0.35 ± 0.02 |
0.94 ± 0.03 a |
0.44 ± 0.02 ab |
0.47 ± 0.02 ab |
0.43 ± 0.01 ab |
|
PRT (mg/g tissue) |
20.36 ± 0.71 |
30.29 ± 1.75 a |
21.54 ± 1.55 b |
18.69 ± 1.71 b |
21.00 ± 1.04 b |
| NO (mg/dL) | 15.84 ± .86 | 42.12 ± 1.70 a | 25.42 ± 1.65 ab | 26.98 ± 1.60 ab | 22.96 ± 1.24 ab |
Values are expressed as Mean ± S. E. M.
a: Significant with control.
b: Significant with lead only group.
c: Significant with Vitamin C group.
d:Significant with Vitamin E group.
Significant at p < 0.05.
The number of animals in each experimental group was 5.