Table 4.
Impact of MTP-493G/T genotype on lipid levels in different area
Group/genotype | n | TC | TG | HDL-C | LDL-C |
---|---|---|---|---|---|
Bama |
2497 |
5.00 ± 1.03d |
1.28 ± 0.86d |
1.57 ± 0.41 |
2.85 ± 0.88d |
TT |
41 |
4.70 ± 0.89 |
1.12 ± 0.45 |
1.44 ± 0.37 |
2.29 ± 0.77 |
GT |
488 |
5.07 ± 1.19a |
1.30 ± 0.92 |
1.58 ± 0.41a |
2.89 ± 1.00b |
GG |
1968 |
4.90 ± 1.00a |
1.28 ± 0.84 |
1.58 ± 0.41a |
2.85 ± 0.85b |
Pingguo |
1197 |
4.38 ± 0.99 |
1.14 ± 0.81 |
1.54 ± 0.38 |
2.32 ± 0.80 |
TT |
15 |
4.29 ± 1.04 |
1.04 ± 0.62 |
1.71 ± 0.49 |
1.81 ± 0.65 |
GT |
261 |
4.42 ± 0.94 |
1.14 ± 0.79 |
1.55 ± 0.41 |
2.35 ± 0.77b |
GG |
921 |
4.37 ± 1.00 |
1.14 ± 0.82 |
1.54 ± 0.37 |
2.32 ± 0.81b |
Total | |||||
TT |
56 |
4.59 ± 0.95 |
1.10 ± 0.50 |
1.51 ± 0.42 |
2.16 ± 0.77 |
GT |
749 |
4.84 ± 1.15a |
1.25 ± 0.88 |
1.57 ± 0.41 |
2.70 ± 0.95b |
GG |
2889 |
4.80 ± 1.03a |
1.23 ± 0.84 |
1.56 ± 0.40 |
2.68 ± 0.87b |
Bama/male |
1413 |
4.96 ± 1.04d |
1.37 ± 1.00c |
1.57 ± 0.44 |
2.77 ± 0.90d |
TT |
24 |
4.68 ± 0.95 |
1.11 ± 0.48 |
1.43 ± 0.38 |
2.11 ± 0.78 |
GT |
261 |
5.01 ± 1.19a |
1.39 ± 1.02 |
1.57 ± 0.45 |
2.80 ± 0.99b |
GG |
1128 |
4.95 ± 1.00 |
1.37 ± 0.99 |
1.56 ± 0.44 |
2.77 ± 0.87b |
Pingguo/male |
725 |
4.46 ± 1.00 |
1.27 ± 0.93 |
1.53 ± 0.37 |
2.35 ± 0.83 |
TT |
11 |
4.10 ± 0.85 |
0.91 ± 0.62 |
1.81 ± 0.53 |
1.66 ± 0.70 |
GT |
142 |
4.56 ± 0.95 |
1.31 ± 0.95 |
1.57 ± 0.41 |
2.40 ± 0.79b |
GG |
572 |
4.44 ± 1.01 |
1.27 ± 0.93 |
1.51 ± 0.36a |
2.35 ± 0.84b |
Total/male | |||||
TT |
35 |
4.49 ± 0.95 |
1.05 ± 0.53 |
1.55 ± 0.46 |
1.97 ± 0.77 |
GT |
403 |
4.85 ± 1.13a |
1.36 ± 0.99 |
1.57 ± 0.44 |
2.66 ± 0.94b |
GG |
1700 |
4.78 ± 1.03a |
1.33 ± 0.97 |
1.55 ± 0.41 |
2.63 ± 0.88b |
Bama/female |
1084 |
5.06 ± 1.02 |
1.16 ± 0.63d |
1.59 ± 0.36 |
2.96 ± 0.85 |
TT |
17 |
4.72 ± 0.84 |
1.12 ± 0.43 |
1.46 ± 0.36 |
2.55 ± 0.71 |
GT |
227 |
5.13 ± 1.18 |
1.21 ± 0.80 |
1.58 ± 0.35 |
3.00 ± 0.98a |
GG |
840 |
5.05 ± 0.97 |
1.15 ± 0.58 |
1.59 ± 0.37 |
2.95 ± 0.81a |
Pingguo/female |
427 |
4.25 ± 0.96 |
0.94 ± 0.52 |
1.56 ± 0.38 |
2.26 ± 0.75 |
TT |
4 |
4.81 ± 1.47 |
1.39 ± 0.49 |
1.44 ± 0.18 |
2.23 ± 0.16 |
GT |
119 |
4.24 ± 0.90 |
0.94 ± 0.48 |
1.53 ± 0.41 |
2.28 ± 0.74 |
GG |
349 |
4.25 ± 0.97 |
0.93 ± 0.53 |
1.57 ± 0.37 |
2.26 ± 0.76 |
Total/female | |||||
TT |
21 |
4.74 ± 0.95 |
1.17 ± 0.45 |
1.45 ± 0.33 |
2.49 ± 0.65 |
GT |
346 |
4.82 ± 1.17 |
1.12 ± 0.72 |
1.57 ± 0.37 |
2.75 ± 0.96 |
GG | 1189 | 4.82 ± 1.04 | 1.09 ± 0.58 | 1.58 ± 0.37 | 2.75 ± 0.85a |
aP < 0.05 and bP < 0.01 in comparison with TT genotype of the same group; cP < 0.05 and dP < 0.01 in comparison between Bama and Pingguo.