Table 1.
Clinical characteristics of patients with and without carotid artery calcification
| All (n = 195) | CAAC (+) (n = 128) | CAAC (−) (n = 67) | p values | |
|---|---|---|---|---|
| Age |
68.8 ± 11.3 |
71.9 ± 9.4 |
62.7 ± 12.3 |
<0.01 |
| Male |
129 (66) |
91 (71) |
38 (57) |
0.046 |
| Hypertension |
171 (88) |
120 (94) |
51 (76) |
<0.01 |
| Diabetes mellitus |
92 (47) |
72 (56) |
20 (30) |
<0.01 |
| Smoking |
110 (56) |
82 (64) |
28 (42) |
<0.01 |
| Dyslipidemia |
146 (75) |
102 (80) |
44 (66) |
0.03 |
| Body mass index (kg/m2) |
22.5 ± 4.5 |
22.3 ± 4.4 |
22.8 ± 4.6 |
0.45 |
| Proteinuria (g/day) |
1.2 (0.3-3.3) |
1.8 (0.3-3.6) |
0.9 (0.3-1.9) |
0.06 |
| C-reactive protein (mg/dL) |
0.09 (0.04-0.22) |
0.09 (0.04-0.24) |
0.09 (0.03-0.19) |
0.22 |
| Hemoglobin (g/dL) |
10.7 ± 2.1 |
10.3 ± 2.0 |
11.4 ± 2.2 |
<0.01 |
| eGFR (ml/min/1.73m2) |
23.2 (14.5-43.8) |
20.0 (13.7-37.2) |
34.3 (17.5-60.2) |
<0.01 |
| Serum corrected calcium (mg/dL) |
9.4 ± 0.5 |
9.5 ± 0.6 |
9.3 ± 0.5 |
0.14 |
| Serum phosphorus (mg/dL) |
3.7 ± 0.7 |
3.8 ± 0.8 |
3.7 ± 0.7 |
0.80 |
| Ca-P product (mg2/dL2) |
35.3 ± 7.0 |
35.6 ± 7.2 |
34.6 ± 6.7 |
0.73 |
| PTH (pg/mL) |
73 (45–117) |
82 (46–125) |
56 (40–88) |
0.03 |
| 1,25(OH)2Vitamin D (pg/mL) |
25 (17–40) |
24 (15–36) |
30 (22–46) |
<0.01 |
| FGF23 (pg/mL) | 64 (41–105) | 73 (48–123) | 50 (36–69) | <0.01 |
Values are expressed as the means ± SD, number (percent), or median (interquartile range).
CAAC carotid artery calcification, eGFR estimated glomerular filtration rate, Ca-P calcium-phosphorus, PTH parathyroid hormone, FGF fibroblast growth factor.