Table 2.
Baseline characteristics of patients at enrolment in the two groups
| Artesunate Mefloquine (n = 157) | Artemether Lumefantrine (n = 153) | p value | |
|---|---|---|---|
| Age (mean ± SD, years) |
25 ± 11 |
23.2 ± 10,5 |
0.15 |
| Weight (mean ± SD, Kg) |
62.1 ± 11.8 |
58.2 ± 11.5 |
0.08 |
| Sex ratio (male/female) |
1.2 |
0.6 |
0.03 |
| Temperature (mean ± SD) |
37.8 ± 1.2 |
37.7 ± 1.1 |
0.41 |
| Median Parasitemia (trophozoites/μL) |
17411 |
17688 |
0.88 |
| Mean haemoglobin (g/dl) |
12.2 ± 1.7 |
11.7 ± 1.7 |
0.99 |
| Anaemia (Hb < 11 g/dl,%) |
36.3 |
40.5 |
0.44 |
| ASAT (UI/L, mean ± SD) |
31.2 ± 18.7 |
33.1 ± 16.8 |
0.38 |
| Patients with normal level of ASAT (ASAT < 40 UI/L) (%) |
128 (81.5%) |
123 (80.4%) |
0.79 |
| ALAT (UI/L, mean ± SD) |
28.2 ± 20.3 |
26.3 ± 24.1 |
0.47 |
| Patients with normal level of ALAT (ALAT < 40 UI/L) (%) |
119 (82.1%) |
138 (90.2%) |
0.04 |
| Creatinine (mean ± SD) |
7.6 ± 5.4 |
8.2 ± 3.5 |
0.24 |
| Patients with normal level of creatinine (<13 mg/L) (%) |
148 (94.3%) |
143 (93.5%) |
0.76 |
| Median Bilirubunemia (mg/L) |
1.91 |
1.71 |
0.51 |
| Patients with normal level of Biliribunemia (<10 mg/L) (%) | 48 (30.6%) | 55 (35.9%) | 0.31 |