Table 1.
Baseline clinical characteristics of study subjects according to E/E’
| Characteristic | Total (n = 115) | E/E’ < 8 (n = 51) | E/E’, 8–12.9 (n = 56) | E/E’ ≥ 13 (n = 8) | p value* |
|---|---|---|---|---|---|
| Age, years |
52.8 ± 8.4 |
50.6 ± 9.2 |
53.9 ± 6.7 |
59.7 ± 11.5 |
0.009 |
| Male sex, n (%) |
78 (67.8) |
38 (74.5) |
38 (67.9) |
2 (25.0) |
0.026 |
| Body mass index, kg/m2 |
24.1 ± 2.9 |
23.1 ± 3.0 |
24.7 ± 2.6 |
26.4 ± 3.3 |
0.002 |
| Systolic blood pressure, mmHg |
120 ± 14 |
115 ± 15 |
123 ± 12 |
130 ± 15 |
0.006 |
| Diastolic blood pressure, mmHg |
73.5 ± 10.6 |
70.5 ± 11.7 |
76.0 ± 8.8 |
75.3 ± 10.4 |
0.022 |
| Total cholesterol, mg/dL |
199 ± 31 |
193 ± 32 |
204 ± 28 |
203 ± 39 |
0.228 |
| Triglyceride, mg/dL |
106 ± 57 |
98 ± 51 |
113 ± 63 |
84 ± 36 |
0.232 |
| LDL-choleterol, mg/dL |
128 ± 29 |
125 ± 28 |
131 ± 28 |
134 ± 35 |
0.449 |
| HDL cholesterol, mg/dL |
50.2 ± 11.4 |
50.8 ± 9.9 |
49.6 ± 12.8 |
52.0 ± 10.5 |
0.786 |
| Fasting plasma glucose, mg/dL |
92.3 ± 12.3 |
90.1 ± 10.6 |
94.9 ± 13.4 |
85.8 ± 9.1 |
0.040 |
| Left ventricular ejection fraction, % |
66.6 ± 5.9 |
66.7 ± 5.6 |
66.5 ± 6.1 |
67.4 ± 5.8 |
0.936 |
| E/A |
1.16 ± 0.36 |
1.25 ± 0.30 |
1.12 ± 0.40 |
0.95 ± 0.25 |
0.035 |
| Deceleration time, ms |
223 ± 47 |
225 ± 52 |
215 ± 40 |
260 ± 40 |
0.037 |
| Left atrial size, mm |
35.4 ± 4.5 |
34.5 ± 4.4 |
36.0 ± 4.8 |
37.2 ± 2.2 |
0.116 |
| E/E’ |
8.77 ± 2.26 |
6.83 ± 0.81 |
9.69 ± 1.26 |
14.01 ± 1.13 |
< 0.001 |
| Mean baPWV, cm/s | 1,325 ± 185 | 1,261 ± 163 | 1,345 ± 169 | 1,569 ± 232 | < 0.001 |
LDL, low density lipoprotein; HDL, high density lipoprotein; baPWV, brachial-ankle pulse wave velocity.
*results from the comparisons among subjects with E/E’ < 8, 8–12.9 and ≥ 13.