Table 1.
MayoGC Phase I studiesa,b(used with permission from Bielinski et al [[12]])
|
Characteristics |
eMERGE Network (PAD)[2] |
GENEVA (VTE)[6] |
PANC[7,8] |
||
|---|---|---|---|---|---|
| Cases (n = 1612) | Controls (n = 1585) | Cases (n = 1233) | Controls (n = 1264) | Controls (n = 613) | |
| Age (y), mean ± SD |
66.0 ± 10.7 |
61.0 ± 7.4 |
55.0 ± 16.2 |
56.0 ± 15.8 |
66.0 ± 10.0 |
| Female (%) |
36 |
40 |
50 |
52 |
45 |
| Medical record length (y) | |||||
| Mean ± SD |
23.4 ± 20.0 |
26.1 ± 20.3 |
13.7 ± 16.3 |
21.1 ± 15.4 |
30.2 ± 16.5 |
| Median ± (range) |
18.7 (1.0–78.6) |
23.0 (1.0–79.2) |
6.3 (1.0–71.8) |
17.8 (1.0–70.2) |
29.8 (1.0–75.0) |
| White (%) |
94 |
94 |
96 |
99 |
100 |
| Geographic location, No. (%)c | |||||
| Olmsted Country |
328(20) |
590(37) |
7(1) |
10(1) |
64(10) |
| Southeast Minnesota |
191(12) |
62(4) |
205(17) |
378(30) |
107(17) |
| Greater Minnesota |
393(24) |
343(22) |
314(25) |
371(25) |
135(22) |
| Iowa |
212(13) |
97(6) |
176(14) |
191(15) |
65(11) |
| South and North Dakota |
50(3) |
31(2) |
79(6) |
71(6) |
19(3) |
| Wisconsin |
128(8) |
68(4) |
121(10) |
138(11) |
32(5) |
| Other states or international | 309(19) | 394(25) | 330(27) | 159(13) | 191(31) |
aeMERGE=Electronic Medical Records and Genomics; GENEVA=Gene Environment Association Studies; MayoGC=Mayo Genome Consortia; PAD=peripheral arterial disease; PANC=Mayo Clinic Molecular Epidemiology of Pancreatic Cancer Study; VTE=venous thromboembolism.
bPercentages may not total 100% because of rounding.
cSoutheast Minnesota includes 7 counties in the southeast corner of Minnesota: Dodge, Goodhoue, Wabasha, Winona, Houston, Fillmore, and Mower, Olmsted County, Minnesota, is a mutually exclusive category.