Figure 8. VopQ and VopS inhibit speck formation by ASC.
A. BMMs from NLRP3-deficient (Nlrp3 −/−) mice were infected with indicated bacteria for one hour, and then immunostained with FITC-labeled anti-ASC antibody (green) and Cy5-labeled anti-V. parahaemolyticus antibody (red). The merged images were shown. Bar, 10 µm. B. Quantitative data of number of speck-forming macrophages in A. Data are presented as the means ± SD of triplicate samples. *p<0.05.