Table 2. Immunodominance of islands, PE/PPE, Esx and T7SS proteins.
% donors responding | % of total response | No. proteins | % of total MTB genome | % Enrichment (% response/% genome) | |
Islands total | 89 | 42.2 | 22 | 0.55 | 76.7 |
Island 1 | 79 | 20.4 | 9 | 0.23 | 88.7 |
Island 2 | 86 | 15.0 | 9 | 0.23 | 65.2 |
Island 3 | 50 | 6.8 | 4 | 0.10 | 68.0 |
PE/PPE total | 71 | 19.2 | 38 | 0.95 | 20.2 |
PE/PPE non-island | 71 | 14.0 | 32 | 0.80 | 17.5 |
PE/PPE island | 46 | 5.2 | 6 | 0.15 | 34.6 |
Esx proteins a total | 75 | 19.6 | 11 | 0.28 | 70.0 |
Esx proteins non-island | 11 | 1.2 | 5 | 0.13 | 9.2 |
Esx proteins island | 75 | 18.5 | 6 | 0.15 | 123.3 |
T7SS b total | 79 | 34.7 | 16 | 0.40 | 86.8 |
T7SS non-island | 39 | 7.0 | 6 | 0.15 | 46.6 |
T7SS island | 75 | 27.7 | 10 | 0.25 | 110.8 |
Other | 82 | 14.2 | 23 | 0.58 | 24.5 |
) Esx proteins include EsxA-W.
) T7SS includes the Esx proteins.