Table 4. Association between air pollution and asthma and wheezing stratified by GSTP1 genotypes in single pollutant model.
| GSTP1 Ile-Ile | GSTP1 Ile-Val or Val-Val | Interaction p-value | |||
| OR | 95% CI | OR | 95% CI | ||
| Asthma | (n = 167/2164) | (n = 84/1138) | |||
| NO2 (8.79 ppb) | 0.88 | 0.64–1.22 | 1.30 | 0.83–2.03 | 0.24 |
| CO (105 ppb) | 1.03 | 0.89–1.20 | 1.11 | 0.90–1.36 | 0.84 |
| SO2 (1.31 ppb) | 0.88 | 0.77–1.01 | 1.06 | 0.89–1.26 | 0.08 |
| PM2.5 (16.84 µg/m3) | 0.60 | 0.45–0.82 | 1.52 | 1.01–2.27 | 0.001 |
| O3 (8.77 ppb) | 0.74 | 0.60–0.90 | 1.19 | 0.91–1.57 | 0.03 |
| Wheezing | (n = 260/2174) | (n = 137/1141) | |||
| NO2 (8.79 ppb) | 1.02 | 0.78–1.32 | 1.15 | 0.80–1.65 | 0.81 |
| CO (105 ppb) | 1.08 | 0.96–1.22 | 1.07 | 0.90–1.27 | 0.67 |
| SO2 (1.31 ppb) | 0.91 | 0.81–1.02 | 1.01 | 0.87–1.16 | 0.26 |
| PM2.5 (16.84 µg/m3) | 0.75 | 0.59–0.96 | 1.24 | 0.89–1.71 | 0.027 |
| O3 (8.77 ppb) | 0.82 | 0.69–0.96 | 1.09 | 0.88–1.82 | 0.049 |
Two-stage hierarchical analysis adjusting for age, sex, parental education, yearly income, during of breast feeding, gestational age, maternal smoking during pregnancy, environmental tobacco smoke, cockroaches note monthly, carpet, pets, home dampness and mold, parental atopy.