Table 5. Association between air pollution and asthma and persistent wheezing stratified by GSTP1 genotypes in two-pollutant models.
| Asthma | model 1 (O3+CO) | model 2 (O3+NO2) | model 3 (O3+SO2) | model 4 (PM10+CO) | model 5 (PM10+NO2) |
| GSTP1: Ile-Ile | |||||
| O3 (8.77 ppb) | 0.72 (0.58–0.89) | 0.72 (0.59–0.88) | 0.76 (0.62–0.94) | ||
| PM2.5 (16.84 µg/m3) | 0.60 (0.45–0.82) | 0.60 (0.44–0.83) | |||
| GSTP1: Ile-Val or Val-Val | |||||
| O3 (8.77 ppb) | 1.30 (0.96–1.77) | 1.24 (0.92–1.66) | 1.18 (0.89–1.57) | ||
| PM2.5 (16.84 µg/m3) | 1.52 (1.01–2.27) | 1.47 (0.97–2.23) | |||
| Wheezing | |||||
| GSTP1: Ile-Ile | |||||
| O3 (8.77 ppb) | 0.83 (0.69–0.98) | 0.81 (0.69–0.96) | 0.84 (0.71–0.99) | ||
| PM2.5 (16.84 µg/m3) | 0.75 (0.59–0.96) | 0.74 (0.57–0.95) | |||
| GSTP1: Ile-Val or Val-Val | |||||
| O3 (8.77 ppb) | 1.14 (0.90–1.45) | 1.10 (0.88–1.38) | 1.11 (0.88–1.40) | ||
| PM2.5 (16.84 µg/m3) | 1.23 (0.89–1.71) | 1.21 (0.86–1.70) |
Two-stage hierarchical analysis adjusting for age, sex, parental education, yearly income, during of breast feeding, gestational age, maternal smoking during pregnancy, environmental tobacco smoke, cockroaches note monthly, carpet, pets, home dampness and mold, parental atopy.